Category: "Column3"

Source : Nature , a Schematic of the mRNA-RBD vaccine design. The SARS-CoV-2 mRNA encodes the signal peptide (SP), receptor-binding domain (RBD) from SARS-CoV-2 strain Wuhan/IVDC-HB-01/2019. b mRNA-RBD was transfected into HEK293T cells. RBD expression in the cell lysate and supernatant was analyzed by western blotting. c Particle size of LNPs by dynamic light scattering. d A representative cryo-electron microscopy image of a LNPs solution following mRNA encapsulation. Scale bar, 100 nm. e Zeta potential for LNPs at pH 4.0 and 7.4

Source : The Lancet , (A) Receptor-binding domain-specific antibodies on day 42, as measured by ELISA, in participants administered with vaccine, by age group and overall, or placebo overall. (B) Neutralising antibodies on day 42, as measured by neutralisation assay with 100 TCID50, in participants administered with vaccine or placebo.

Sources: Sheva, Pettersson, Duke, UN

Source : Medrxiv (A) daily confirmed COVI 19 cases reported in Geneva up to July 1st, 2020. (B) Daily number of recruited households over the 12-week study period.

Source: Reuters

Source : Medrxiv

Source : AJNR A. Patient-side robot with articulating arm for stroke treatment. B. Lead-shielded console with monitors and controls.

Source: NYT

Source : Science

Source: CDC, CNBC

Source : Biorxiv , (A) The region in which the amino acid 614 was localized (square) on the trimer of Spike molecules (B) Predicted residue interactions with electrostatic (middle panels) and lipophibic (right panels) properties were compared between Spike D614 and G614 variants. (C) Sera from COVID-19 patients developing mild (blue, n=17), moderate (green, n=13) (D) Percentage of patients with decreased seropositivity against D614 and G614 variants from the different groups were presented.

Source: Wikipedia

Source : Indian Ministry of Health and Family Welfare

Source : ScienceMag

Source : News Medical A) Schematic of vaccine components which were RBD-Fe, S1-Fe and ECD-Fe. Fe: Ferritin, RBD: receptor-binding domain, ECD: ectodomain. (B) Schematic of nanoparticle of the three vaccines. PyMOL software was used for visualization14. (C) Western Blot analysis of the products prepared in silkworm by using an anti-RBD antibody. (D) ELISA of the S proteins to evaluate the expression levels. ECD-Fe with 287 ug/mL larval haemolymph, S1-Fe with 468 ug/mL larval haemolymph, RBD-Fe with 187 ug/mL larval haemolymph. (E) TEM image and two-dimensional (2D) reconstruction confirmed the successful assembly of each nanoparticle, IEM confirmed the S protein on the surface of the nanoparticle.

Source : AJNR , A, NCCT on the day of admission demonstrates subtle findings of acute ischemia in the right MCA (arrowheads) and bilateral ACA (arrows) territories, including hypoattenuation and loss of gray-white differentiation. B, Repeat NCCT on hospital day 2 demonstrates progression of acute infarcts in the right MCA and bilateral ACA territories, including worsening edema and mass effect.

Source : The COVID Tracking Project

Source: MapBox